The Kaneka Ubiquinol® Advantage
Backed by Science. Trusted by 200+ Brands.
Kaneka has been the leader in coenzyme Q10 (CoQ10) research and innovation for 50 years, setting the global standard for quality, safety, and efficacy. As the premier supplier of CoQ10 ingredients worldwide, we’ve worked to advance the scientific understanding of conventional CoQ10 and its active antioxidant form, ubiquinol.
Tell your patients to look for the Kaneka Quality Seal.
Tell your patients to look for the Kaneka Quality Seal.
Tell your patients to look for the Kaneka Quality Seal.
Tell your patients to look for the Kaneka Quality Seal.
Kaneka Ubiquinol® Stands Apart From Conventional CoQ10 Supplements
Ubiquinol, a lipid-soluble antioxidant, is concentrated where reactive oxygen species are formed1-5
Developed for enhanced absorption, Kaneka Ubiquinol® is the active antioxidant form of CoQ10.1,2 In the body, ubiquinol is concentrated in the mitochondrial lipid membrane, where reactive oxygen species (ROS) are formed. This makes it an ideal antioxidant to neutralize potentially harmful ROS.2-5
Unlike a conventional CoQ10 (ubiquinone) supplement, which must be converted in the body before it can function as an antioxidant, Kaneka Ubiquinol® performs its antioxidant functions without requiring conversion.6,7
Ubiquinol, a lipid-soluble antioxidant, is concentrated where reactive oxygen species are formed1-5
Developed for enhanced absorption, Kaneka Ubiquinol® is the active antioxidant form of CoQ10.1,2 In the body, ubiquinol is concentrated in the mitochondrial lipid membrane, where reactive oxygen species (ROS) are formed. This makes it an ideal antioxidant to neutralize potentially harmful ROS.2-5
Unlike a conventional CoQ10 (ubiquinone) supplement, which must be converted in the body before it can function as an antioxidant, Kaneka Ubiquinol® performs its antioxidant functions without requiring conversion.6,7
Unlike a conventional CoQ10 (ubiquinone) supplement, which must be converted in the body before it can function as an antioxidant, Kaneka Ubiquinol® performs its antioxidant functions without requiring conversion.6,7
2x better absorbed than a conventional CoQ10 supplement8
*Approximate increase in healthy adults with 200 mg Kaneka Ubiquinol® daily for 30 days.9
Switching patients from conventional CoQ10 supplements to a Kaneka Ubiquinol® supplement offers enhanced bioavailability and measurable increases in plasma ubiquinol levels. Research in healthy adults demonstrates that 200 mg of Kaneka Ubiquinol® taken daily for at least 30 days increases plasma ubiquinol levels by approximately 8x over baseline.9
This direct, efficient support for cellular energy generation and antioxidant defense sets Kaneka Ubiquinol® apart for healthcare providers seeking reliable, science-backed ubiquinol supplementation.
*Approximate increase in healthy adults with 200 mg Kaneka Ubiquinol® daily for 30 days.9
Conventional CoQ10 supplements vs Kaneka Ubiquinol® Supplements
| Conventional CoQ10 (Ubiquinone) Supplements | Kaneka Ubiquinol® Supplements | |
| Antioxidant Form1,2 | No | Yes |
| Conversion Required for Transport in Blood6,7 | Yes, must be converted to ubiquinol for transport in blood | No conversion required for transport in blood |
| Conversion Required for Energy Synthesis | Ubiquinone must accept electrons to proceed in the electron transport chain. | Ubiquinol is preformatted for immediate activity in the electron transport chain. |
| Absorption8 | Lower absorption than ubiquinol | Superior absorption, up to 2x better absorbed than conventional CoQ10 |
| Antioxidant Activity6,7 | Requires conversion for antioxidant function | Already in antioxidant state, ready to provide direct antioxidant support and neutralize free radicals |
| Bioidentical to Human Form | Yes, but may contain synthetic isomers not found in the human body. Not all ubiquinone supplements are synthesized to have reduced levels of impurities. | Yes, Kaneka Ubiquinol® contains a form bioidentical to that made in the human body. It contains the fewest impurities and is the purest form of ubiquinol. |
| Ingredient-Specific Clinical Studies | Varies by ingredient manufacturer and brand | 85+ published human clinical studies using Kaneka Ubiquinol® |
| Years of Experience in Marketplace | Varies by brand | Nearly 2 decades of consumer experience in the US alone |
| Brand Trust | Varies by brand | Trusted by 200+ consumer and physician supplement brands |
| Made in USA | No | Yes |
Commitment to Quality
Commitment to Quality
Kaneka Ubiquinol® is manufactured in a state-of-the-art, 47-acre facility in Pasadena, Texas, where rigorous quality controls and secure systems are maintained at every stage of production. Our dedicated team of quality assurance professionals oversees each batch to ensure Kaneka Ubiquinol® meets the highest industry standards for purity, potency, and consistency.
The result is a ubiquinol supplement ingredient with a well-established safety profile, demonstrated by extensive research data and consumer experience worldwide. Kaneka’s commitment to quality means you can recommend Kaneka Ubiquinol® with confidence, knowing your patients receive a product that is reliable, traceable, and backed by decades of Kaneka’s scientific leadership.
Give Your Patients the Kaneka Ubiquinol® Advantage
Tell your patients to look for the Kaneka Quality Seal
Help your patients identify supplements formulated with Kaneka Ubiquinol®, the most studied and trusted form of ubiquinol available.
Advise patients to look for the Kaneka Quality Seal, featured on the label of more than 200 dietary supplement brands containing Kaneka Ubiquinol®. This mark signifies a commitment to scientific rigor, product purity, and clinical reliability.
By recommending Kaneka Ubiquinol®, you help your patients choose a supplement backed by decades of research, extensive clinical validation, and industry-leading quality standards.
Give Your Patients the Kaneka Ubiquinol® Advantage
Tell your patients to look for the Kaneka Quality Seal
Help your patients identify supplements formulated with Kaneka Ubiquinol®, the most studied and trusted form of ubiquinol available.
Advise patients to look for the Kaneka Quality Seal, featured on the label of more than 200 dietary supplement brands containing Kaneka Ubiquinol®. This mark signifies a commitment to scientific rigor, product purity, and clinical reliability.
By recommending Kaneka Ubiquinol®, you help your patients choose a supplement backed by decades of research, extensive clinical validation, and industry-leading quality standards.
Kaneka Ubiquinol® is clinically validated to deliver measurable impact across key domains of patient health. From cardiovascular support to promoting mitochondrial health, recommending Kaneka Ubiquinol® empowers healthcare providers to address the nutritional and wellness needs of patients at every adult stage of life.
Explore uses for Kaneka Ubiquinol®
REFERENCES: 1. Littarru GP, Tiano L. Bioenergetic and antioxidant properties of coenzyme Q10: recent developments. Mol Biotechnol. 2007;37(1):31-37. 2. Ernster L, Forsmark-Andrée P. Ubiquinol: an endogenous antioxidant in aerobic organisms. Clin Investig. 1993;71(8 Suppl):S60-S65. 3. Bratic A, Larsson NG. The role of mitochondria in aging. J Clin Invest. 2013;123(3):951-957. 4. Pallotti F, Bergamini C, Lamperti C, Fato R. The roles of coenzyme Q in disease: direct and indirect involvement in cellular functions. Int J Mol Sci. 2021;23(1):128. 5. Bentinger M, Brismar K, Dallner G. The antioxidant role of coenzyme Q. Mitochondrion. 2007;7(suppl):S41-S50. 6. Kubo H, Yamamoto Y, Fujisawa A. Orally ingested ubiquinol-10 or ubiquinone-10 reaches the intestinal tract and is absorbed by the small intestine of mice mostly in its original form. J Clin Biochem Nutr. 2023;72(2):101-106. 7. Sabbatinelli J, Orlando P, Galeazzi R, et al. Ubiquinol ameliorates endothelial dysfunction in subjects with mild-to-moderate dyslipidemia: a randomized clinical trial. Nutrients. 2020;12(4):1098. 8. Langsjoen PH, Langsjoen AM. Comparison study of plasma coenzyme Q10 levels in healthy subjects supplemented with ubiquinol versus ubiquinone. Clin Pharmacol Drug Dev. 2014;3(1):13-17. 9. Hosoe K, Kitano M, Kishida H, et al. Study on safety and bioavailability of ubiquinol (Kaneka QH) after single and 4-week multiple oral administration to healthy volunteers. Regul Toxicol Pharmacol. 2007;47(1):19-28.